{"id":62555,"date":"2025-07-09T12:45:03","date_gmt":"2025-07-09T10:45:03","guid":{"rendered":"https:\/\/mivisalud.com\/blog\/neuromodulation-innovation-for-the-treatment-of-refractory-pain\/"},"modified":"2025-10-29T10:28:28","modified_gmt":"2025-10-29T09:28:28","slug":"neuromodulation-innovation-for-the-treatment-of-refractory-pain","status":"publish","type":"post","link":"https:\/\/mivisalud.com\/en\/blog\/neuromodulation-innovation-for-the-treatment-of-refractory-pain\/","title":{"rendered":"Neuromodulation: Innovation for the treatment of refractory pain"},"content":{"rendered":"<h2>What is neuromodulation?<\/h2>\n<p style=\"font-weight: 400;\">Neuromodulation is a form of treatment that modifies the activity of the nervous system through the application of electrical stimuli or the controlled administration of drugs. These treatments act directly on the nerve pathways responsible for pain, with the aim of reducing or even eliminating it. <\/p>\n<p>Instead of blocking pain with drugs, neuromodulation acts on its source, interfering with the nerve signals that cause it. And the best part: in many cases it can be adjusted, customized or even reversed if it doesn&#8217;t work as expected. <\/p>\n<h2>When is it recommended?<\/h2>\n<p style=\"font-weight: 400;\">These therapies are mainly used in people with refractory chronic pain, that is, pain that has not improved despite having tried analgesics, physiotherapy, infiltrations or other techniques.<\/p>\n<p>Among the most frequent situations are:<br \/>\n&#8211; Pain after spinal surgery (failed surgery syndrome)<br \/>\n&#8211; Neuropathic pain (due to nerve damage)<br \/>\n&#8211; Complex oncologic pain<br \/>\n&#8211; Complex regional pain (CRPS)<br \/>\n&#8211; Severe neuralgia (such as trigeminal neuralgia)<br \/>\n&#8211; Pain after amputations or spinal cord injuries<\/p>\n<h2>Types of neuromodulation: beyond the spinal cord<\/h2>\n<h3>Stimulation of posterior cords of the spinal cord<\/h3>\n<p style=\"font-weight: 400;\">It consists of implanting small electrodes in the epidural space to send electrical impulses that &#8220;block&#8221; the pain signal before it reaches the brain.<br \/>\nIdeal for pain in the back, legs or arms, it has proven to be effective in many patients.<\/p>\n<h3>Dorsal root ganglion stimulation (DRG)<\/h3>\n<p style=\"font-weight: 400;\">It allows a more precise and focal stimulation, ideal for difficult areas such as the groin, foot or knee. It is useful when the pain is very localized or when other forms have not been effective. <\/p>\n<h3>Thalamic or cortical stimulation<\/h3>\n<p style=\"font-weight: 400;\">In very severe cases, such as pain after a stroke, areas of the brain such as the thalamus or the motor cortex are stimulated. These are more complex techniques and reserved for very specific cases. <\/p>\n<h3>Intrathecal infusion of drugs<\/h3>\n<p style=\"font-weight: 400;\">A catheter is implanted and connected to a pump that delivers drugs directly into the fluid surrounding the spinal cord. Fewer side effects and greater efficacy with very small doses. <\/p>\n<h3>Peripheral nerve stimulation<\/h3>\n<p style=\"font-weight: 400;\">Directly stimulates peripheral nerves such as the sciatic. Useful in localized pain after surgery or trauma. <\/p>\n<h3>Transcranial magnetic stimulation (TMS)<\/h3>\n<p style=\"font-weight: 400;\">Non-invasive, magnetic fields are applied to the brain. Useful for fibromyalgia, central neuropathic pain and more. Its effects are not permanent, but can be repeated without significant side effects.  <\/p>\n<h2>What innovations are there in these treatments?<\/h2>\n<p style=\"font-weight: 400;\">Some recent improvements include:<br \/>\n&#8211; Smaller, more discreet devices<br \/>\n&#8211; Stimulation without paresthesia<br \/>\n&#8211; Control from mobile or tablet<br \/>\n&#8211; MRI compatibility<br \/>\n&#8211; Long-life or rechargeable batteries<\/p>\n<h2>What are the benefits of neuromodulation?<\/h2>\n<p style=\"font-weight: 400;\">&#8211; Pain reduction (50% or more improvement)<br \/>\n&#8211; Reduced need for medication<br \/>\n&#8211; Increased physical activity<br \/>\n&#8211; Improved sleep and mood<br \/>\n&#8211; Customized and adjustable treatment<\/p>\n<h2>Are there any risks?<\/h2>\n<p style=\"font-weight: 400;\">Although it is generally safe, there may be complications such as:<br \/>\n&#8211; Infection or hematomas<br \/>\n&#8211; Migration of the electrode<br \/>\n&#8211; Pain in the area of the generator<br \/>\n&#8211; Need for replacement or reprogramming<br \/>\n&#8211; In rare cases, lack of efficiency<\/p>\n<h2>In a nutshell<\/h2>\n<p style=\"font-weight: 400;\">Neuromodulation represents one of the great revolutions in the treatment of refractory chronic pain. Today we have multiple ways of acting directly on the nervous system to reduce suffering and improve quality of life. <\/p>\n<p>At MIVI, our commitment is to offer you the most advanced options, adapted to your particular situation, with a human, close and multidisciplinary approach.<\/p>\n<p><strong><a href=\"https:\/\/mivisalud.com\/en\/physician\/isaac-pena-vergara\/\">MEET DOCTOR ISAAC PE\u00d1A  <\/a> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-399 alignright\" src=\"https:\/\/mivisalud.com\/wp-content\/uploads\/2023\/09\/isaac-pena-jefe-unidad-sevilla-huelva.jpg\" alt=\"Isaac Pe\u00f1a. head of the pain unit Mivi Seville and Huelva.\" width=\"184\" height=\"138\"><\/strong><\/p>\n<hr>\n<p style=\"font-weight: 400;\">Member No.: 414116984<\/p>\n<p style=\"font-weight: 400;\">Centers:<\/p>\n<ul style=\"font-weight: 400;\">\n<li><a href=\"https:\/\/mivisalud.com\/en\/center\/mivi-huelva-pain-unit\/\">MIVI Huelva Pain Unit<\/a><\/li>\n<\/ul>\n<p style=\"font-weight: 400;\">Dr. Isaac Pe\u00f1a Vergara is a specialist in Anesthesiology and Chronic Pain Treatment, and is the director of the Pain Unit of MIVI Salud in Huelva and Seville.<\/p>\n<p style=\"font-weight: 400;\">He currently coordinates the Functional Unit of Chronic Refractory Pain at the Virgen del Rocio University Hospital since 2018.<\/p>\n<p style=\"font-weight: 400;\">He has extensive training: among other degrees, he has a specialty in Anesthesiology and Resuscitation, a Master&#8217;s Degree in Pain Treatment from the University of Seville, and a Fellowship in Interventional Pain Practice (FIPP) from the World Institute of Pain in New York.<\/p>\n<hr>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is neuromodulation? Neuromodulation is a form of treatment that modifies the activity of the nervous system through&hellip;<\/p>\n","protected":false},"author":3,"featured_media":61712,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1295],"tags":[],"class_list":["post-62555","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-treatments"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u25b7 Neuromodulation: Innovation for the treatment of refractory pain | Mivi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mivisalud.com\/en\/blog\/neuromodulation-innovation-for-the-treatment-of-refractory-pain\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u25b7 Neuromodulation: Innovation for the treatment of refractory pain | Mivi\" \/>\n<meta property=\"og:description\" content=\"What is neuromodulation? Neuromodulation is a form of treatment that modifies the activity of the nervous system through&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mivisalud.com\/en\/blog\/neuromodulation-innovation-for-the-treatment-of-refractory-pain\/\" \/>\n<meta property=\"og:site_name\" content=\"Mivi\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-09T10:45:03+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-29T09:28:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mivisalud.com\/wp-content\/uploads\/2025\/06\/Neuromodulacion-Innovacion-para-el-tratamiento-del-dolor-refractario-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1478\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Irene Juan Valdeolmillos\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" 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